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Fulton Family Psychiatry

Low Testosterone- Effects On Depression In Men

Key takeaways on how low testosterone effecting depression in men:


1. Testosterone can increase serotonin and suppress cortisol, thereby acting as an

antidepressant

2. Low-testosterone induced depression would likely present with low libido, low

energy, negative self-esteem and poor stress tolerance

3. TRT should be used for mild depression in middle aged men with test-confirmed

hypogonadism who is refractory to antidepressants and psychotherapy



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